RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
miR-20a-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
ROCK2
Pathway
NF-KAPPA B SIGNALING PATHWAY
PubMed ID
Title
"MiR-20a-5p overexpression prevented diabetic cardiomyopathy via inhibition of cardiomyocyte apoptosis, hypertrophy, fibrosis and JNK/NF-kappaB signalling pathway"
Year
2021
Function
"MiR-20a-5p may effectively ameliorate diabetic cardiomyopathy through improving cardiac metabolism, and subsequently inhibiting inflammation, apoptosis, hypertrophy, fibrosis and JNK/NF-KAPPA B pathway via modulating ROCK2."